Astragaloside IV restrains pyroptosis and fibrotic development of pulmonary artery smooth muscle cells to ameliorate pulmonary artery hypertension through the PHD2/HIF1α signaling pathway

BACKGROUND: Astragaloside (AS)-IV, extracted from traditional Chinese medicine Astragalus mongholicus, has been widely used in the anti-inflammatory treatment for cardiovascular disease. However, the mechanism by which AS-IV affects pulmonary artery hypertension (PAH) development remains largely unk...

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Detalles Bibliográficos
Autores principales: Xi, Jie, Ma, Yan, Liu, Dongmei, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568875/
https://www.ncbi.nlm.nih.gov/pubmed/37828459
http://dx.doi.org/10.1186/s12890-023-02660-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568875/
https://www.ncbi.nlm.nih.gov/pubmed/37828459
http://dx.doi.org/10.1186/s12890-023-02660-9

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