Engineering endosomolytic nanocarriers of diverse morphologies using confined impingement jet mixing

The clinical translation of many biomolecular therapeutics has been hindered by undesirable pharmacokinetic (PK) properties, inadequate membrane permeability, poor endosomal escape and cytosolic delivery, and/or susceptibility to degradation. Overcoming these challenges merits the development of nan...

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Detalles Bibliográficos
Autores principales: Pagendarm, Hayden M., Stone, Payton T., Kimmel, Blaise R., Baljon, Jessalyn J., Aziz, Mina H., Pastora, Lucinda E., Hubert, Lauren, Roth, Eric W., Almunif, Sultan, Scott, Evan A., Wilson, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568979/
https://www.ncbi.nlm.nih.gov/pubmed/37753868
http://dx.doi.org/10.1039/d3nr02874g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568979/
https://www.ncbi.nlm.nih.gov/pubmed/37753868
http://dx.doi.org/10.1039/d3nr02874g

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