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Synaptic remodeling of GluA1 and GluA2 expression in the nucleus accumbens promotes susceptibility to cognitive deficits concomitant with downstream GSK3β mediated neurotoxicity in female mice during abstinence from voluntary oral methamphetamine

Stimulant-use disorders can present with long-term cognitive and mental health deficits. Little is known about the underlying molecular mechanisms perpetuating sex differences in cognitive and behavioral deficits in preclinical models of addiction to stimulants such as methamphetamine (MA). The curr...

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Detalles Bibliográficos
Autores principales: Memos, Nicoletta, Avila, Jorge A., Rodriguez, Edgar, Serrano, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569060/
https://www.ncbi.nlm.nih.gov/pubmed/37842014
http://dx.doi.org/10.1016/j.addicn.2023.100112