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Conditional activation of an anti-IgM antibody-drug conjugate for precise B cell lymphoma targeting

Cancerous B cells are almost indistinguishable from their non-malignant counterparts regarding their surface antigen expression. Accordingly, the challenge to be faced consists in elimination of the malignant B cell population while maintaining a functional adaptive immune system. Here, we present a...

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Detalles Bibliográficos
Autores principales: Schoenfeld, Katrin, Harwardt, Julia, Habermann, Jan, Elter, Adrian, Kolmar, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569071/
https://www.ncbi.nlm.nih.gov/pubmed/37841262
http://dx.doi.org/10.3389/fimmu.2023.1258700