Aptamer Conformational Dynamics Modulate Neurotransmitter Sensing in Nanopores

[Image: see text] Aptamers that undergo conformational changes upon small-molecule recognition have been shown to gate the ionic flux through nanopores by rearranging the charge density within the aptamer-occluded orifice. However, mechanistic insight into such systems where biomolecular interaction...

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Detalles Bibliográficos
Autores principales: Stuber, Annina, Douaki, Ali, Hengsteler, Julian, Buckingham, Denis, Momotenko, Dmitry, Garoli, Denis, Nakatsuka, Nako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569099/
https://www.ncbi.nlm.nih.gov/pubmed/37721359
http://dx.doi.org/10.1021/acsnano.3c05377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569099/
https://www.ncbi.nlm.nih.gov/pubmed/37721359
http://dx.doi.org/10.1021/acsnano.3c05377

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