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Aptamer Conformational Dynamics Modulate Neurotransmitter Sensing in Nanopores
[Image: see text] Aptamers that undergo conformational changes upon small-molecule recognition have been shown to gate the ionic flux through nanopores by rearranging the charge density within the aptamer-occluded orifice. However, mechanistic insight into such systems where biomolecular interaction...
Autores principales: | Stuber, Annina, Douaki, Ali, Hengsteler, Julian, Buckingham, Denis, Momotenko, Dmitry, Garoli, Denis, Nakatsuka, Nako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569099/ https://www.ncbi.nlm.nih.gov/pubmed/37721359 http://dx.doi.org/10.1021/acsnano.3c05377 |
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