Nuciferine induces autophagy to relieve vascular cell adhesion molecule 1 activation via repressing the Akt/mTOR/AP1 signal pathway in the vascular endothelium

Pro-inflammatory factor-associated vascular cell adhesion molecule 1 (VCAM1) activation initiates cardiovascular events. This study aimed to explore the protective role of nuciferine on TNFα-induced VCAM1 activation. Nuciferine was administrated to both high-fat diet (HFD)-fed mice and the TNFα-expo...

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Detalles Bibliográficos
Autores principales: Wei, Haibin, Yin, Yujie, Yang, Wenwen, Zhu, Jinyan, Chen, Lin, Guo, Rui, Yang, Zhen, Li, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569124/
https://www.ncbi.nlm.nih.gov/pubmed/37841916
http://dx.doi.org/10.3389/fphar.2023.1264324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569124/
https://www.ncbi.nlm.nih.gov/pubmed/37841916
http://dx.doi.org/10.3389/fphar.2023.1264324

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