The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D(2) Agonist [18F]MCL-524

The dopamine D(2) agonist MCL-524 is selective for the D(2) receptor in the high-affinity state (D(2)(high)), and, therefore, the PET analogue, [(18)F]MCL-524, may facilitate the elucidation of the role of D(2)(high) in disorders such as schizophrenia. However, the previously reported synthesis of [...

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Detalles Bibliográficos
Autores principales: Inkster, James A. H., Sromek, Anna W., Akurathi, Vamsidhar, Neumeyer, John L., Packard, Alan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569134/
https://www.ncbi.nlm.nih.gov/pubmed/37830058
http://dx.doi.org/10.3390/chemistry3030075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569134/
https://www.ncbi.nlm.nih.gov/pubmed/37830058
http://dx.doi.org/10.3390/chemistry3030075

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