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Presenilin 2 N141I Mutation Induces Hyperimmunity by Immune Cell-specific Suppression of REV-ERBα without Altering Central Circadian Rhythm

Circadian rhythm is a 24-hour cycle of behavioral and physiological changes. Disrupted sleep-wake patterns and circadian dysfunction are common in patients of Alzheimer Disease (AD) and are closely related with neuroinflammation. However, it is not well known how circadian rhythm of immune cells is...

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Detalles Bibliográficos
Autores principales: Nam, Hyeri, Kim, Boil, Lee, Younghwan, Choe, Han Kyoung, Yu, Seong-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569138/
https://www.ncbi.nlm.nih.gov/pubmed/37749927
http://dx.doi.org/10.5607/en23012