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Glutamatergic synaptic deficits in the prefrontal cortex of the Ts65Dn mouse model for Down syndrome

Down syndrome (DS), the most prevalent cause of intellectual disability, stems from a chromosomal anomaly resulting in an entire or partial extra copy of chromosome 21. This leads to intellectual disability and a range of associated symptoms. While there has been considerable research focused on the...

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Detalles Bibliográficos
Autores principales: Thomazeau, Aurore, Lassalle, Olivier, Manzoni, Olivier J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569174/
https://www.ncbi.nlm.nih.gov/pubmed/37841687
http://dx.doi.org/10.3389/fnins.2023.1171797