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TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly

Localization of a variety of RNAs to non-membrane-bound cellular compartments such as nucleoli and Cajal bodies is critical for their stability and function. The molecular mechanisms that underly the recruitment and exclusion of RNAs from these phase-separated organelles is incompletely understood....

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Detalles Bibliográficos
Autores principales: Klump, Basma M., Perez, Gloria I., Patrick, Eric M., Adams-Boone, Kate, Cohen, Scott B., Han, Li, Yu, Kefei, Schmidt, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569210/
https://www.ncbi.nlm.nih.gov/pubmed/37267110
http://dx.doi.org/10.1016/j.celrep.2023.112577