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The untapped potential of targeting NRF2 in neurodegenerative disease

Since its initial discovery almost three decades ago, the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) has been shown to regulate a host of downstream transcriptional responses and play a critical role in preventing or promoting disease progression depending on the context...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Tai, Dodson, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569223/
https://www.ncbi.nlm.nih.gov/pubmed/37840813
http://dx.doi.org/10.3389/fragi.2023.1270838