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Biomimetic on-chip assay reveals the anti-metastatic potential of a novel thienopyrimidine compound in triple-negative breast cancer cell lines

Introduction: This study presents a microfluidic tumor microenvironment (TME) model for evaluating the anti-metastatic efficacy of a novel thienopyrimidines analog with anti-cancer properties utilizing an existing commercial platform. The microfluidic device consists of a tissue compartment flanked...

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Detalles Bibliográficos
Autores principales: Sigdel, Indira, Ofori-Kwafo, Awurama, Heizelman, Robert J., Nestor-Kalinoski, Andrea, Prabhakarpandian, Balabhaskar, Tiwari, Amit K., Tang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569307/
https://www.ncbi.nlm.nih.gov/pubmed/37840664
http://dx.doi.org/10.3389/fbioe.2023.1227119