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Leishmania braziliensis exosomes activate human macrophages to produce proinflammatory mediators

Exosomes, organelles measuring 30-200nm, are secreted by various cell types. Leishmania exosomes consist of many proteins, including heat shock proteins, annexins, Glycoprotein 63, proteins exerting signaling activity and those containing mRNA and miRNA. Studies have demonstrated that Leishmania don...

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Detalles Bibliográficos
Autores principales: Peixoto, Fabio C., Zanette, Dalila L., Cardoso, Thiago M., Nascimento, Mauricio T., Sanches, Rodrigo C. O., Aoki, Mateus, Scott, Phillip, Oliveira, Sérgio C., Carvalho, Edgar M., Carvalho, Lucas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569463/
https://www.ncbi.nlm.nih.gov/pubmed/37841240
http://dx.doi.org/10.3389/fimmu.2023.1256425