Upregulated Fcrl5 disrupts B cell anergy causes autoimmune disease

B cell anergy plays a critical role in maintaining self-tolerance by inhibiting autoreactive B cell activation to prevent autoimmune diseases. Here, we demonstrated that Fc receptor-like 5 (Fcrl5) upregulation contributes to autoimmune disease pathogenesis by disrupting B cell anergy. Fcrl5—a gene w...

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Detalles Bibliográficos
Autores principales: Ono, Chisato, Tanaka, Shinya, Myouzen, Keiko, Iwasaki, Takeshi, Ueda, Mahoko, Oda, Yoshinao, Yamamoto, Kazuhiko, Kochi, Yuta, Baba, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569490/
https://www.ncbi.nlm.nih.gov/pubmed/37841260
http://dx.doi.org/10.3389/fimmu.2023.1276014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569490/
https://www.ncbi.nlm.nih.gov/pubmed/37841260
http://dx.doi.org/10.3389/fimmu.2023.1276014

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