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Predicting regional somatic mutation rates using DNA motifs

How the locus-specificity of epigenetic modifications is regulated remains an unanswered question. A contributing mechanism is that epigenetic enzymes are recruited to specific loci by DNA binding factors recognizing particular sequence motifs (referred to as epi-motifs). Using these motifs to predi...

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Detalles Bibliográficos
Autores principales: Liu, Cong, Wang, Zengmiao, Wang, Jun, Liu, Chengyu, Wang, Mengchi, Ngo, Vu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569533/
https://www.ncbi.nlm.nih.gov/pubmed/37782656
http://dx.doi.org/10.1371/journal.pcbi.1011536