Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin that reflect nucleosome organisation

High-throughput sequencing technology is central to our current understanding of the human methylome. The vast majority of studies use chemical conversion to analyse bulk-level patterns of DNA methylation across the genome from a population of cells. While this technology has been used to probe sing...

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Detalles Bibliográficos
Autores principales: Kerr, Lyndsay, Kafetzopoulos, Ioannis, Grima, Ramon, Sproul, Duncan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569558/
https://www.ncbi.nlm.nih.gov/pubmed/37782664
http://dx.doi.org/10.1371/journal.pgen.1010958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569558/
https://www.ncbi.nlm.nih.gov/pubmed/37782664
http://dx.doi.org/10.1371/journal.pgen.1010958

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