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Newly discovered genomic mutation patterns in radiation-induced small intestinal tumors of Apc(Min/+) mice

Among the small intestinal tumors that occur in irradiated mice of the established mouse model B6/B6-Chr18(MSM)-F1 Apc(Min/+), loss of heterozygosity analysis can be utilized to estimate whether a deletion in the wild-type allele containing the Adenomatous polyposis coli (Apc) region (hereafter refe...

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Detalles Bibliográficos
Autores principales: Iizuka, Daisuke, Sasatani, Megumi, Ishikawa, Atsuko, Daino, Kazuhiro, Hirouchi, Tokuhisa, Kamiya, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569626/
https://www.ncbi.nlm.nih.gov/pubmed/37824459
http://dx.doi.org/10.1371/journal.pone.0292643