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Borderline rpoB mutations transmit at the same rate as common rpoB mutations in a tuberculosis cohort in Bangladesh

The spread of multidrug-resistant tuberculosis (MDR-TB) is a growing problem in many countries worldwide. Resistance to one of the primary first-line drugs, rifampicin, is caused by mutations in the Mycobacterium tuberculosis rpoB gene. So-called borderline rpoB mutations confer low-level resistance...

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Detalles Bibliográficos
Autores principales: Lempens, Pauline, Van Deun, Armand, Aung, Kya J. M., Hossain, Mohammad A., Behruznia, Mahboobeh, Decroo, Tom, Rigouts, Leen, de Jong, Bouke C., Meehan, Conor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569737/
https://www.ncbi.nlm.nih.gov/pubmed/37750750
http://dx.doi.org/10.1099/mgen.0.001109