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ATP protects anti-PD-1/radiation-induced cardiac dysfunction by inhibiting anti-PD-1 exacerbated cardiomyocyte apoptosis, and improving autophagic flux

The synergy between radiotherapy and immunotherapy in treating thoracic cancers presents a potent therapeutic advantage, yet it also carries potential risks. The extent and nature of cumulative cardiac toxicity remain uncertain, prompting the need to discern its mechanisms and devise effective mitig...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhao, Jing, Meng, Zhijun, Guo, Rui, Yang, Ruihong, Liu, Caihong, Gao, Jia, Xie, Yaoli, Jiao, Xiangying, Fang, Heping, Zhao, Jianli, Wang, Yajing, Cao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570000/
https://www.ncbi.nlm.nih.gov/pubmed/37842574
http://dx.doi.org/10.1016/j.heliyon.2023.e20660