On the rules of engagement for microRNAs targeting protein coding regions

MiRNAs post-transcriptionally repress gene expression by binding to mRNA 3′UTRs, but the extent to which they act through protein coding regions (CDS regions) is less well established. MiRNA interaction studies show a substantial proportion of binding occurs in CDS regions, however sequencing studie...

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Detalles Bibliográficos
Autores principales: Sapkota, Sunil, Pillman, Katherine A, Dredge, B Kate, Liu, Dawei, Bracken, Julie M, Kachooei, Saba Ataei, Chereda, Bradley, Gregory, Philip A, Bracken, Cameron P, Goodall, Gregory J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570018/
https://www.ncbi.nlm.nih.gov/pubmed/37522357
http://dx.doi.org/10.1093/nar/gkad645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570018/
https://www.ncbi.nlm.nih.gov/pubmed/37522357
http://dx.doi.org/10.1093/nar/gkad645

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