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DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation

Faithful cell division is the basis for the propagation of life and DNA replication must be precisely regulated. DNA replication stress is a prominent endogenous source of genome instability that not only leads to ageing, but also neuropathology and cancer development in humans. Specifically, the is...

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Detalles Bibliográficos
Autores principales: Kingsley, Georgia, Skagia, Aggeliki, Passaretti, Paolo, Fernandez-Cuesta, Cyntia, Reynolds-Winczura, Alicja, Koscielniak, Kinga, Gambus, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570026/
https://www.ncbi.nlm.nih.gov/pubmed/37638758
http://dx.doi.org/10.1093/nar/gkad694