ZEB1 promotes non-homologous end joining double-strand break repair

Repair of DSB induced by IR is primarily carried out by Non-Homologous End Joining (NHEJ), a pathway in which 53BP1 plays a key role. We have discovered that the EMT-inducing transcriptional repressor ZEB1 (i) interacts with 53BP1 and that this interaction occurs rapidly and is significantly amplifi...

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Detalles Bibliográficos
Autores principales: Genetta, Thomas L, Hurwitz, Joshua C, Clark, Evan A, Herold, Benjamin T, Khalil, Shadi, Abbas, Tarek, Larner, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570029/
https://www.ncbi.nlm.nih.gov/pubmed/37665026
http://dx.doi.org/10.1093/nar/gkad723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570029/
https://www.ncbi.nlm.nih.gov/pubmed/37665026
http://dx.doi.org/10.1093/nar/gkad723

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