Assessing in vivo the impact of gene context on transcription through DNA supercoiling

Gene context can have significant impact on gene expression but is currently not integrated in quantitative models of gene regulation despite known biophysical principles and quantitative in vitro measurements. Conceptually, the simplest gene context consists of a single gene framed by two topologic...

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Detalles Bibliográficos
Autores principales: Boulas, Ihab, Bruno, Lisa, Rimsky, Sylvie, Espeli, Olivier, Junier, Ivan, Rivoire, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570042/
https://www.ncbi.nlm.nih.gov/pubmed/37667073
http://dx.doi.org/10.1093/nar/gkad688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570042/
https://www.ncbi.nlm.nih.gov/pubmed/37667073
http://dx.doi.org/10.1093/nar/gkad688

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