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Assessing in vivo the impact of gene context on transcription through DNA supercoiling
Gene context can have significant impact on gene expression but is currently not integrated in quantitative models of gene regulation despite known biophysical principles and quantitative in vitro measurements. Conceptually, the simplest gene context consists of a single gene framed by two topologic...
Autores principales: | Boulas, Ihab, Bruno, Lisa, Rimsky, Sylvie, Espeli, Olivier, Junier, Ivan, Rivoire, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570042/ https://www.ncbi.nlm.nih.gov/pubmed/37667073 http://dx.doi.org/10.1093/nar/gkad688 |
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