Translocating RNA polymerase generates R-loops at DNA double-strand breaks without any additional factors

The R-loops forming around DNA double-strand breaks (DSBs) within actively transcribed genes play a critical role in the DSB repair process. However, the mechanisms underlying R-loop formation at DSBs remain poorly understood, with diverse proposed models involving protein factors associated with RN...

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Detalles Bibliográficos
Autores principales: Lim, Gunhyoung, Hwang, Seungha, Yu, Kilwon, Kang, Jin Young, Kang, Changwon, Hohng, Sungchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570047/
https://www.ncbi.nlm.nih.gov/pubmed/37638763
http://dx.doi.org/10.1093/nar/gkad689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570047/
https://www.ncbi.nlm.nih.gov/pubmed/37638763
http://dx.doi.org/10.1093/nar/gkad689

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