Widespread effects of DNA methylation and intra-motif dependencies revealed by novel transcription factor binding models

Several studies suggested that transcription factor (TF) binding to DNA may be impaired or enhanced by DNA methylation. We present MeDeMo, a toolbox for TF motif analysis that combines information about DNA methylation with models capturing intra-motif dependencies. In a large-scale study using ChIP...

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Detalles Bibliográficos
Autores principales: Grau, Jan, Schmidt, Florian, Schulz, Marcel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570048/
https://www.ncbi.nlm.nih.gov/pubmed/37650641
http://dx.doi.org/10.1093/nar/gkad693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570048/
https://www.ncbi.nlm.nih.gov/pubmed/37650641
http://dx.doi.org/10.1093/nar/gkad693

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