Cargando…
Widespread effects of DNA methylation and intra-motif dependencies revealed by novel transcription factor binding models
Several studies suggested that transcription factor (TF) binding to DNA may be impaired or enhanced by DNA methylation. We present MeDeMo, a toolbox for TF motif analysis that combines information about DNA methylation with models capturing intra-motif dependencies. In a large-scale study using ChIP...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570048/ https://www.ncbi.nlm.nih.gov/pubmed/37650641 http://dx.doi.org/10.1093/nar/gkad693 |