Stability and mechanism of threose nucleic acid toward acid-mediated degradation

Xeno-nucleic acids (XNAs) have gained significant interest as synthetic genetic polymers for practical applications in biomedicine, but very little is known about their biophysical properties. Here, we compare the stability and mechanism of acid-mediated degradation of α-l-threose nucleic acid (TNA)...

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Detalles Bibliográficos
Autores principales: Lee, Erica M, Setterholm, Noah A, Hajjar, Mohammad, Barpuzary, Bhawna, Chaput, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570051/
https://www.ncbi.nlm.nih.gov/pubmed/37650628
http://dx.doi.org/10.1093/nar/gkad716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570051/
https://www.ncbi.nlm.nih.gov/pubmed/37650628
http://dx.doi.org/10.1093/nar/gkad716

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