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A novel splice variant of the human MSTN gene encodes a myostatin‐specific myostatin inhibitor

BACKGROUND: Myostatin, encoded by the MSTN gene comprising 3 exons, is a potent negative regulator of skeletal muscle growth. Although a variety of myostatin inhibitors have been invented for increasing muscle mass in muscle wasting diseases, no effective inhibitor is currently available for clinica...

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Detalles Bibliográficos
Autores principales: Maeta, Kazuhiro, Farea, Manal, Nishio, Hisahide, Matsuo, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570081/
https://www.ncbi.nlm.nih.gov/pubmed/37582652
http://dx.doi.org/10.1002/jcsm.13314