Cargando…

AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia

BACKGROUND: Sarcopenia, an age‐related loss of muscle mass, is a critical factor that affects the health of the older adults. The SOD1KO mouse is deficient of Cu/Zn superoxide dismutase, used as an accelerated aging model. We previously showed that NT‐3 improves muscle fibre size by activating the m...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Lingying, Ozes, Burcak, Moss, Kyle, Myers, Morgan, Ridgley, Alicia, Sahenk, Zarife
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570084/
https://www.ncbi.nlm.nih.gov/pubmed/37553101
http://dx.doi.org/10.1002/jcsm.13303