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Radiation induces long‐term muscle fibrosis and promotes a fibrotic phenotype in fibro‐adipogenic progenitors

BACKGROUND: Radiation‐induced muscle pathology, characterized by muscle atrophy and fibrotic tissue accumulation, is the most common debilitating late effect of therapeutic radiation exposure particularly in juvenile cancer survivors. In healthy muscle, fibro/adipogenic progenitors (FAPs) are requir...

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Detalles Bibliográficos
Autores principales: Collao, Nicolas, D'Souza, Donna, Messeiller, Laura, Pilon, Evan, Lloyd, Jessica, Larkin, Jillian, Ngu, Matthew, Cuillerier, Alexanne, Green, Alexander E., Menzies, Keir J., Burelle, Yan, De Lisio, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570115/
https://www.ncbi.nlm.nih.gov/pubmed/37671686
http://dx.doi.org/10.1002/jcsm.13320