Cargando…

Radiation induces long‐term muscle fibrosis and promotes a fibrotic phenotype in fibro‐adipogenic progenitors

BACKGROUND: Radiation‐induced muscle pathology, characterized by muscle atrophy and fibrotic tissue accumulation, is the most common debilitating late effect of therapeutic radiation exposure particularly in juvenile cancer survivors. In healthy muscle, fibro/adipogenic progenitors (FAPs) are requir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Collao, Nicolas, D'Souza, Donna, Messeiller, Laura, Pilon, Evan, Lloyd, Jessica, Larkin, Jillian, Ngu, Matthew, Cuillerier, Alexanne, Green, Alexander E., Menzies, Keir J., Burelle, Yan, De Lisio, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570115/ https://www.ncbi.nlm.nih.gov/pubmed/37671686 http://dx.doi.org/10.1002/jcsm.13320

Ejemplares similares

Role of Metabolic Stress and Exercise in Regulating Fibro/Adipogenic Progenitors
por: Collao, Nicolas, et al.
Publicado: (2020)

Resistance and endurance exercise training improves muscle mass and the inflammatory/fibrotic transcriptome in a rhabdomyosarcoma model
por: Collao, Nicolas, et al.
Publicado: (2023)

Grx2 Regulates Skeletal Muscle Mitochondrial Structure and Autophagy
por: Liaghati, Ava, et al.
Publicado: (2021)

Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration
por: Reggio, Alessio, et al.
Publicado: (2020)

Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors
por: Cerquone Perpetuini, Andrea, et al.
Publicado: (2020)

Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases
por: Molina, Thomas, et al.
Publicado: (2021)

Fibro–Adipogenic Progenitors Cross-Talk in Skeletal Muscle: The Social Network
por: Biferali, Beatrice, et al.
Publicado: (2019)

Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis
por: Marinkovic, Milica, et al.
Publicado: (2019)

Matrix stiffness and architecture drive fibro-adipogenic progenitors’ activation into myofibroblasts
por: Loomis, Taryn, et al.
Publicado: (2022)

Determinants of epigenetic resistance to HDAC inhibitors in dystrophic fibro‐adipogenic progenitors
por: Consalvi, Silvia, et al.
Publicado: (2022)

Denervation Drives YAP/TAZ Activation in Muscular Fibro/Adipogenic Progenitors
por: Gallardo, Felipe S., et al.
Publicado: (2023)

MME(+) fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle
por: Fitzgerald, Gillian, et al.
Publicado: (2023)

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva
por: Lees-Shepard, John B., et al.
Publicado: (2018)

Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors
por: Kang, Xia, et al.
Publicado: (2018)

Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy
por: Malecova, Barbora, et al.
Publicado: (2018)

Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration
por: Zhao, Liang, et al.
Publicado: (2020)

Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors
por: Saito, Yuki, et al.
Publicado: (2020)

SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
por: Giuliani, Giulio, et al.
Publicado: (2021)

Senescent fibro-adipogenic progenitors are potential drivers of pathology in inclusion body myositis
por: Nelke, Christopher, et al.
Publicado: (2023)

Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes
por: Liu, Mengyao, et al.
Publicado: (2023)

Fluorescence-activated cell sorting and phenotypic characterization of human fibro-adipogenic progenitors
por: Billeskov, Tine Borum, et al.
Publicado: (2023)

Characterization of adipocytes derived from fibro/adipogenic progenitors resident in human skeletal muscle
por: Arrighi, N, et al.
Publicado: (2015)

Muscle-derived fibro-adipogenic progenitor cells for production of cultured bovine adipose tissue
por: Dohmen, Richard G. J., et al.
Publicado: (2022)

Origins, potency, and heterogeneity of skeletal muscle fibro-adipogenic progenitors—time for new definitions
por: Contreras, Osvaldo, et al.
Publicado: (2021)

Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors
por: Kotsaris, Georgios, et al.
Publicado: (2023)

The Late Effects of Radiation Therapy on Skeletal Muscle Morphology and Progenitor Cell Content are Influenced by Diet-Induced Obesity and Exercise Training in Male Mice
por: D’Souza, Donna, et al.
Publicado: (2019)

Increased Fibro-Adipogenic Progenitors and Intramyocellular Lipid Accumulation in Obesity-Related Skeletal Muscle Dysfunction
por: Jia, Guanghong, et al.
Publicado: (2019)

Evolving Roles of Muscle-Resident Fibro-Adipogenic Progenitors in Health, Regeneration, Neuromuscular Disorders, and Aging
por: Theret, Marine, et al.
Publicado: (2021)

Adherent muscle connective tissue fibroblasts are phenotypically and biochemically equivalent to stromal fibro/adipogenic progenitors
por: Contreras, Osvaldo, et al.
Publicado: (2019)

Muscle fibro-adipogenic progenitors from a single-cell perspective: Focus on their “virtual” secretome
por: Negroni, Elisa, et al.
Publicado: (2022)

A 3D adipogenesis platform to study the fate of fibro/adipogenic progenitors in muscular dystrophies
por: Reggio, Alessio, et al.
Publicado: (2023)

Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle
por: Uapinyoying, Prech, et al.
Publicado: (2023)

Selective ablation of Nfix in macrophages attenuates muscular dystrophy by inhibiting fibro‐adipogenic progenitor‐dependent fibrosis
por: Saclier, Marielle, et al.
Publicado: (2022)

Diverse effector and regulatory functions of fibro/adipogenic progenitors during skeletal muscle fibrosis in muscular dystrophy
por: Wang, Xingyu, et al.
Publicado: (2022)

AMP‐activated protein kinase inhibition in fibro‐adipogenic progenitors impairs muscle regeneration and increases fibrosis
por: Liu, Xiangdong, et al.
Publicado: (2022)

A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress
por: Picard, Martin, et al.
Publicado: (2018)

ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers
por: Gonzalez, David, et al.
Publicado: (2017)

An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice
por: Lees-Shepard, John B., et al.
Publicado: (2022)

Depletion of CD206(+) M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration
por: Nawaz, Allah, et al.
Publicado: (2022)

Muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury
por: Sesillo, Francesca Boscolo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m09b3933phtecd6h4dgjev4r3d