O-GlcNAc transferase promotes glioblastoma by modulating genes responsible for cell survival, invasion, and inflammation

Metabolic reprogramming has emerged as one of the key hallmarks of cancer cells. Various metabolic pathways are dysregulated in cancers, including the hexosamine biosynthesis pathway. Protein O-GlcNAcylation is catalyzed by the enzyme O-GlcNAc transferase (OGT), an effector of hexosamine biosynthesi...

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Detalles Bibliográficos
Autores principales: Sheikh, Muhammad Abid, Alawathugoda, Thilina T., Vyas, Garima, Emerald, Bright Starling, Ansari, Suraiya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570119/
https://www.ncbi.nlm.nih.gov/pubmed/37689115
http://dx.doi.org/10.1016/j.jbc.2023.105235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570119/
https://www.ncbi.nlm.nih.gov/pubmed/37689115
http://dx.doi.org/10.1016/j.jbc.2023.105235

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