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TXNL1 has dual functions as a redox active thioredoxin-like protein as well as an ATP- and redox-independent chaperone

TXNL1 (also named TRP32, for thioredoxin related protein of 32 kDa) is a cytosolic thioredoxin-fold protein expressed in all cell types and conserved from yeast to mammals, but with yet poorly known function. Here, we expressed and purified human TXNL1 together with several Cys-to-Ser variants, char...

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Detalles Bibliográficos
Autores principales: Andor, Attila, Mohanraj, Mahendravarman, Pató, Zsuzsanna Anna, Úri, Katalin, Biri-Kovács, Beáta, Cheng, Qing, Arnér, Elias S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570131/
https://www.ncbi.nlm.nih.gov/pubmed/37804695
http://dx.doi.org/10.1016/j.redox.2023.102897