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PI3K signaling through a biochemical systems lens

Following 3 decades of extensive research into PI3K signaling, it is now evidently clear that the underlying network does not equate to a simple ON/OFF switch. This is best illustrated by the multifaceted nature of the many diseases associated with aberrant PI3K signaling, including common cancers,...

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Detalles Bibliográficos
Autores principales: Madsen, Ralitsa R., Toker, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570132/
https://www.ncbi.nlm.nih.gov/pubmed/37673340
http://dx.doi.org/10.1016/j.jbc.2023.105224