The VCAM1–ApoE pathway directs microglial chemotaxis and alleviates Alzheimer’s disease pathology

In Alzheimer’s disease (AD), sensome receptor dysfunction impairs microglial danger-associated molecular pattern (DAMP) clearance and exacerbates disease pathology. Although extrinsic signals, including interleukin-33 (IL-33), can restore microglial DAMP clearance, it remains largely unclear how the...

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Detalles Bibliográficos
Autores principales: Lau, Shun-Fat, Wu, Wei, Wong, Hiu Yi, Ouyang, Li, Qiao, Yi, Xu, Jiahui, Lau, Jessica Hiu-Yan, Wong, Carlton, Jiang, Yuanbing, Holtzman, David M., Fu, Amy K. Y., Ip, Nancy Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570140/
https://www.ncbi.nlm.nih.gov/pubmed/37735240
http://dx.doi.org/10.1038/s43587-023-00491-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570140/
https://www.ncbi.nlm.nih.gov/pubmed/37735240
http://dx.doi.org/10.1038/s43587-023-00491-1

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