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Transcriptional and epigenetic decoding of the microglial aging process

As important immune cells, microglia undergo a series of alterations during aging that increase the susceptibility to brain dysfunctions. However, the longitudinal characteristics of microglia remain poorly understood. In this study, we mapped the transcriptional and epigenetic profiles of microglia...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyu, Li, Yuxin, Jin, Yuxiao, Zhang, Yuheng, Wu, Jingchuan, Xu, Zhen, Huang, Yubin, Cai, Lin, Gao, Shuai, Liu, Taohui, Zeng, Fanzhuo, Wang, Yafei, Wang, Wenxu, Yuan, Ti-Fei, Tian, Hengli, Shu, Yousheng, Guo, Feifan, Lu, Wei, Mao, Ying, Mei, Xifan, Rao, Yanxia, Peng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570141/
https://www.ncbi.nlm.nih.gov/pubmed/37697166
http://dx.doi.org/10.1038/s43587-023-00479-x