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ADAR1 exacerbates ischemic brain injury via astrocyte-mediated neuron apoptosis
Astrocytes affect stroke outcomes by acquiring functionally dominant phenotypes. Understanding molecular mechanisms dictating astrocyte functional status after brain ischemia/reperfusion may reveal new therapeutic strategies. Adenosine deaminase acting on RNA (ADAR1), an RNA editing enzyme, is not n...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570147/ https://www.ncbi.nlm.nih.gov/pubmed/37801857 http://dx.doi.org/10.1016/j.redox.2023.102903 |