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ADAR1 exacerbates ischemic brain injury via astrocyte-mediated neuron apoptosis

Astrocytes affect stroke outcomes by acquiring functionally dominant phenotypes. Understanding molecular mechanisms dictating astrocyte functional status after brain ischemia/reperfusion may reveal new therapeutic strategies. Adenosine deaminase acting on RNA (ADAR1), an RNA editing enzyme, is not n...

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Detalles Bibliográficos
Autores principales:	Cai, Dunpeng, Fraunfelder, Mikayla, Fujise, Ken, Chen, Shi-You
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570147/ https://www.ncbi.nlm.nih.gov/pubmed/37801857 http://dx.doi.org/10.1016/j.redox.2023.102903

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