Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma

Palmitic acid (PA) is the most common fatty acid in humans and mediates palmitoylation through its conversion into palmitoyl coenzyme A. Although palmitoylation affects many proteins, its pathophysiological functions are only partially understood. Here we demonstrate that PA acts as a molecular chec...

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Detalles Bibliográficos
Autores principales: Jeong, Do-Won, Park, Jong-Wan, Kim, Kyeong Seog, Kim, Jiyoung, Huh, June, Seo, Jieun, Kim, Ye Lee, Cho, Joo-Youn, Lee, Kwang-Woong, Fukuda, Junji, Chun, Yang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570296/
https://www.ncbi.nlm.nih.gov/pubmed/37828054
http://dx.doi.org/10.1038/s41467-023-42170-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570296/
https://www.ncbi.nlm.nih.gov/pubmed/37828054
http://dx.doi.org/10.1038/s41467-023-42170-0

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