Polarity protein AF6 functions as a modulator of necroptosis by regulating ubiquitination of RIPK1 in liver diseases

AF6, a known polarity protein, contributes to the maintenance of homeostasis while ensuring tissue architecture, repair, and integrity. Mice that lack AF6 display embryonic lethality owing to cell–cell junction disruption. However, we show AF6 promotes necroptosis via regulating the ubiquitination o...

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Detalles Bibliográficos
Autores principales: Xinyu, Wang, Qian, Wen, Yanjun, Wu, Jingwen, Kong, Keying, Xu, Jiazheng, Jiao, Haibing, Zhang, Kai, Wang, Xiao, Xu, Lixing, Zhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570300/
https://www.ncbi.nlm.nih.gov/pubmed/37828052
http://dx.doi.org/10.1038/s41419-023-06170-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570300/
https://www.ncbi.nlm.nih.gov/pubmed/37828052
http://dx.doi.org/10.1038/s41419-023-06170-8

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