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Biocatalytic characterization of an alcohol dehydrogenase variant deduced from Lactobacillus kefir in asymmetric hydrogen transfer

Hydrogen transfer biocatalysts to prepare optically pure alcohols are in need, especially when it comes to sterically demanding ketones, whereof the bioreduced products are either essential precursors of pharmaceutically relevant compounds or constitute APIs themselves. In this study, we report on t...

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Detalles Bibliográficos
Autores principales: Rudzka, Aleksandra, Zdun, Beata, Antos, Natalia, Montero, Lia Martínez, Reiter, Tamara, Kroutil, Wolfgang, Borowiecki, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570314/
https://www.ncbi.nlm.nih.gov/pubmed/37828252
http://dx.doi.org/10.1038/s42004-023-01013-1