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Kidney tubular epithelial cells control interstitial fibroblast fate by releasing TNFAIP8-encapsulated exosomes

Kidney fibrosis, characterized by the activation and expansion of the matrix-producing fibroblasts, is the common outcome of chronic kidney disease (CKD). While fibroblast proliferation is well studied in CKD, little is known about the regulation and mechanism of fibroblast depletion. Here, we show...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Liu, Zhao, Wang, Cong, Miao, Jinhua, Zhou, Shan, Ren, Qian, Jia, Nan, Zhou, Lili, Liu, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570316/
https://www.ncbi.nlm.nih.gov/pubmed/37828075
http://dx.doi.org/10.1038/s41419-023-06209-w