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Increased Ca2 + transport across the mitochondria-associated membranes by Mfn2 inhibiting endoplasmic reticulum stress in ischemia/reperfusion kidney injury

Renal ischemia/reperfusion (I/R) injury, which leads to acute kidney injury (AKI), is a major cause of morbidity and mortality in a variety of clinical situations. This study aimed to investigate the protective role of Mfn2 during renal I/R injury. Overexpression of Mfn2 in NRK-52E rat renal tubular...

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Detalles Bibliográficos
Autores principales: Wang, Shun, Sang, Xiaohong, Li, Suhua, Yang, Wenjun, Wang, Shihan, Chen, Haixia, Lu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570331/
https://www.ncbi.nlm.nih.gov/pubmed/37828353
http://dx.doi.org/10.1038/s41598-023-44538-0