Rare antibody phage isolation and discrimination (RAPID) biopanning enables identification of high-affinity antibodies against challenging targets

In vitro biopanning platforms using synthetic phage display antibody libraries have enabled the identification of antibodies against antigens that were once thought to be beyond the scope of immunization. Applying these methods against challenging targets remains a critical challenge. Here, we prese...

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Detalles Bibliográficos
Autores principales: Chung, Dong hee, Kong, Sophie, Young, Nicholas J., Chuo, Shih-Wei, Shiah, Jamie V., Connelly, Emily J., Rohweder, Peter J., Born, Alexandra, Manglik, Aashish, Grandis, Jennifer R., Johnson, Daniel E., Craik, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570357/
https://www.ncbi.nlm.nih.gov/pubmed/37828150
http://dx.doi.org/10.1038/s42003-023-05390-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570357/
https://www.ncbi.nlm.nih.gov/pubmed/37828150
http://dx.doi.org/10.1038/s42003-023-05390-0

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