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Rare antibody phage isolation and discrimination (RAPID) biopanning enables identification of high-affinity antibodies against challenging targets
In vitro biopanning platforms using synthetic phage display antibody libraries have enabled the identification of antibodies against antigens that were once thought to be beyond the scope of immunization. Applying these methods against challenging targets remains a critical challenge. Here, we prese...
Autores principales: | Chung, Dong hee, Kong, Sophie, Young, Nicholas J., Chuo, Shih-Wei, Shiah, Jamie V., Connelly, Emily J., Rohweder, Peter J., Born, Alexandra, Manglik, Aashish, Grandis, Jennifer R., Johnson, Daniel E., Craik, Charles S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570357/ https://www.ncbi.nlm.nih.gov/pubmed/37828150 http://dx.doi.org/10.1038/s42003-023-05390-0 |
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