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Molecular mechanism of decision-making in glycosaminoglycan biosynthesis

Two major glycosaminoglycan types, heparan sulfate (HS) and chondroitin sulfate (CS), control many aspects of development and physiology in a type-specific manner. HS and CS are attached to core proteins via a common linker tetrasaccharide, but differ in their polymer backbones. How core proteins ar...

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Detalles Bibliográficos
Autores principales: Sammon, Douglas, Krueger, Anja, Busse-Wicher, Marta, Morgan, Rhodri Marc, Haslam, Stuart M., Schumann, Benjamin, Briggs, David C., Hohenester, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570366/
https://www.ncbi.nlm.nih.gov/pubmed/37828045
http://dx.doi.org/10.1038/s41467-023-42236-z