Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin

Insulin is proved to have angiogenic ability thereby may worsen the diabetic retinopathy (DR) progression. Insulin also triggers the expression of endogenous angiogenic peptide, apelin. Since protamine was introduced as an inhibitor of the apelin receptor, we hypothesized that use of protaminated in...

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Detalles Bibliográficos
Autores principales: Yeganeh-Hajahmadi, Mahboobeh, Mehrabani, Mehrnaz, Esmaili, Mojdeh, Farokhi, Mitra Shadkam, Sanjari, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570368/
https://www.ncbi.nlm.nih.gov/pubmed/37828117
http://dx.doi.org/10.1038/s41598-023-44639-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570368/
https://www.ncbi.nlm.nih.gov/pubmed/37828117
http://dx.doi.org/10.1038/s41598-023-44639-w

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