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Protamine as a barrier against the angiogenic effect of insulin: a possible role of apelin
Insulin is proved to have angiogenic ability thereby may worsen the diabetic retinopathy (DR) progression. Insulin also triggers the expression of endogenous angiogenic peptide, apelin. Since protamine was introduced as an inhibitor of the apelin receptor, we hypothesized that use of protaminated in...
Autores principales: | Yeganeh-Hajahmadi, Mahboobeh, Mehrabani, Mehrnaz, Esmaili, Mojdeh, Farokhi, Mitra Shadkam, Sanjari, Mojgan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10570368/ https://www.ncbi.nlm.nih.gov/pubmed/37828117 http://dx.doi.org/10.1038/s41598-023-44639-w |
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